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Clinical outcomes from the PARAMEDIC2 trial are summarized, showing higher rates of ROSC in the epinephrine group (36.3%) compared with placebo (11.7%), a modest increase in 30-day survival, but a higher proportion of survivors with severe neurological impairment (31.0% vs

Uh, but the mechanism makes sense because of its effect on glucose disposal, that it would help preserve muscle glycogen

Recently, we found that NRF2 regulates the serine biosynthesis pathway through ATF4 and PHGDH, which led to an independence from exogenous serine sources [43]